Chronic Inflammatory Bowel Disease & Anemia |
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Description
Chronic inflammatory bowel disease is a group of chronic diseases that are complicated with anemia. The prevalence of anemia in patients with the disease ranges from 8.8% to 73.7% depending on the patient subpopulation. Also, one third of inflammatory bowel disease patients suffer from recurrent anaemia.
Anemia is shown to be an indicator of the severity of disease, and has significant impact on the quality of life The anemia may be due to excessive production of cytokines and leukotrines that interfere with the effect of erythropoietin (EPO) at the bone marrow, and the release of stored iron in the reticuloendothelial system. It may also be due to chronic blood loss
Reference
Am J Med. 2004 Apr 5;116 Suppl 7A:44S-49S. "Prevalence and outcomes of anemia in inflammatory bowel disease: a systematic review of the literature.", Wilson A, Reyes E, Ofman J., Zynx Health, Beverly Hills, California 90212, USA.
Clin Lab Haematol. 2001 Feb;23(1):1-6. "The pathological consequences of anaemia."; Silverberg DS, Iaina A, Wexler D, Blum M.; Department of Nephrology, Tel Aviv Medical Center, Tel Aviv, Israel.
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