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Alternative Name
Anemia - hemolytic due to G6PD deficiency, Hemolytic anemia due to G6PD deficiency
Description
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Nature's essence™ Blood Tonic Syrup
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Our Price: 18.95
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The Blood Tonic Syrup promotes production of the blood cells from the bone marrow. Thus, it can help to conpensate loss of blood cells due to hemolysis. When the marrow is able to compensate, anemia does not occur.
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G-6-PD deficiency (Glucose-6-phosphate dehydrogenase deficiency) is a subtype of hemolytic anemia. It is hereditary, sex-linked enzyme defect. When the person is exposed to stress of infection or certain types of drugs, chemicals, the enzyme defect results in breakdown of red blood cells, leads to anemia.
Symptoms
Symtpoms of hemolytic anemia - G-6-PD deficiency include:
Dark urine,
Enlarged spleen,
Fatigue,
Paleness,
Rapid heart rate,
Shortness of breath,
Yellow skin color (jaundice) ,
Cause
The primary effect of G-6-PD deficiency is the reduction of the enzyme G-6-PD in red blood cells, causing hemolysis (destruction of the cells), which leads to anemia -- either acute hemolytic or a chronic spherocytic type.
Without the red blood cells exposed to an oxidant or stress, people with the disorder are not normally anemic and display no evidence of the disease.
Drugs that can bring on this reaction include:
antimalarial agents,
aspirin,
nitrofurantoin,
nonsteroidal anti-inflammatory drugs (NSAIDs),
quinidine,
quinine,
sulfonamides (antibiotic) ,
It can also be caused by exposure to certain chemicals, such as those in mothballs. The chronic spherocytic anemia is unaffected by exposure to these drugs.
Newly produced (young) red blood cells have normal G6PD activity. So, episodes are usually brief. Risk group
In the United States, many more black than white people have the disorder. Approximately 10-14% of the black male population is affected. The disorder may occasionally affect a black women to a mild degree (depending on their genetic inheritance). Another type of this disorder can occur in whites of Mediterranean descent. which is also associated with acute episodes of hemolysis
Reference
Medline, Medical Encyclopedia, the National Library of Medicine of USA
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